Atypical hemolytic uremic syndrome: diagnosis, management, and discontinuation of therapy.

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy typically characterized by anemia, thrombocytopenia, and end-organ injury. aHUS occurs due to endothelial injury resulting from overactivation of the alternative pathway of the complement system. The etiology of the dysregulated complement system is either a genetic mutation in 1 or more complement proteins or an acquired deficiency due to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Atypical Hemolytic Uremic Syndrome
• Share to Autoantibodies
• Share to Complement System Proteins