[Atypical hemolytic uremic syndrome].

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy, characterized by microangiopathic hemolytic anemia, thrombocytopenia and renal involvement. It causes end stage renal disease requiring dialysis in most affected patients. It mainly affects young adults (contrary to what was thought years ago). When aHUS is primary, the cause is a genetic mutation in the alternative complement...

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• Antibodies, Monoclonal, Humanized
• Atypical Hemolytic Uremic Syndrome
• Kidney Transplantation
• Mutation