Article
Atypical hemolytic uremic syndrome: update on the complement system and what is new.
Nephron. Clinical practice - 1 Jan 2010
Hirt-Minkowski Patricia, Dickenmann Michael, Schifferli Jürg A
Abstract excerpt
Atypical hemolytic uremic syndrome (aHUS) is a rare disease of microangiopathic hemolytic anemia, thrombocytopenia, and predominant renal impairment. It is characterized by the absence of Shiga toxin-producing bacteria as a triggering factor. During the last decade, aHUS has been demonstrated to be a disorder of the complement alternative pathway dysregulation, as there is a growing list of mutations and...
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