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Article

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling.

Developmental biology - 1 Jul 2013

Wang Feng, Hu Wanzhou, Xian Jian, Ohnuma Shin-ichi, Brenton James D

Abstract excerpt

Tgfbi, a fasciclin family extracellular matrix protein, has various roles in human diseases from corneal dystrophies to cancer. However, the molecular mechanisms that underlie its functions are poorly understood. Here, we studied the role of Tgfbi during Xenopus embryogenesis. During gastrulation and immediately after, Xtgfbi is expressed at developmentally important signaling centers including the dorsal...

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PMID: 23246513
DOI: 10.1016/j.ydbio.2012.11.010

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DLD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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