Article
High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast.
Genome research - 1 Apr 2013
Liachko Ivan, Youngblood Rachel A, Keich Uri, Dunham Maitreya J
Abstract excerpt
DNA replication origins are necessary for the duplication of genomes. In addition, plasmid-based expression systems require DNA replication origins to maintain plasmids efficiently. The yeast autonomously replicating sequence (ARS) assay has been a valuable tool in dissecting replication origin structure and function. However, the dearth of information on origins in diverse yeasts limits the availability of...
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