Article
The ApoE-Null Golden Hamster: A Novel Model of Atherosclerosis.
Cardiovascular toxicology - 29 Jul 2026
Fang Guangming, Zheng Shiyue, Miao Jinxin, Zeng Yi, Peng Ying, Zhai Yafei, Guo Haoran, Wang Jianyao, Dong Yiming, Tian Xiaoxu, Liu Mengduan, Liu Yangyang, Li Xiaowei, Wang Mengyu, Zhao Xiaoyan, Du Jie, Wang Yaohe, Dong Jianzeng
Abstract excerpt
Atherosclerosis is a chronic, progressive arterial disease characterized by the deposition of lipids on the inner arterial walls, leading to plaque formation and serious cardiovascular events. Traditional mouse models of atherosclerosis require prolonged dietary induction to exhibit arterial lesions due to significant differences in lipid metabolism compared to humans. In contrast, Golden hamsters share a lipid...
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