Article

Lipid lowering alone fails to limit atherosclerosis progression and neutrophilic inflammation in middle-aged mice

2025-11-05

Abstract excerpt

While cholesterol lowering remains the cornerstone therapy for atherosclerosis and prevention of major adverse cardiovascular events, 33–50% of individuals on lipid-lowering therapy continue to exhibit elevated inflammation. Middle age (MA) represents a critical window for disease acceleration, underscoring a need to better understand non-resolving inflammation in this time frame. We rendered young (2 months) and...

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Literature Corpus work: bed28a74-b44d-5c6d-863c-77a2ce54fba3
DOI: 10.1101/2025.11.04.686598

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