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Article

The heritability of oxycodone reward and concomitant phenotypes in a LG/J × SM/J mouse advanced intercross line.

Addiction biology - 1 Jul 2014

Bryant Camron D, Guido Michael A, Kole Loren A, Cheng Riyan

Abstract excerpt

The rewarding property of opioids likely contributes to their abuse potential. Therefore, determining the genetic basis of opioid reward could aid in understanding the neurobiological mechanisms of opioid addiction, provided that it is a heritable trait. Here, we characterized the rewarding property of the widely abused prescription opioid oxycodone (OXY) in the conditioned place preference (CPP) assay using LG/J...

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Source

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Identifiers

PMID: 23231598
DOI: 10.1111/adb.12016
PMCID: PMC4300855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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