Article
Variability in prescription opioid intake and reinforcement amongst 129 substrains.
Genes, brain, and behavior - 1 Sept 2017
Jimenez S M, Healy A F, Coelho M A, Brown C N, Kippin T E, Szumlinski K K
Abstract excerpt
Opioid abuse in the United States has reached epidemic proportions, with treatment admissions and deaths associated with prescription opioid abuse quadrupling over the past 10 years. Although genetics are theorized to contribute substantially to inter-individual variability in the development, severity and treatment outcomes of opioid abuse/addiction, little direct preclinical study has focused on the behavioral...
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