Article
Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus.
Clinical and vaccine immunology : CVI - 1 Feb 2013
Qian Feng, Bolen Christopher R, Jing Chunxia, Wang Xiaomei, Zheng Wei, Zhao Hongyu, Fikrig Erol, Bruce R Douglas, Kleinstein Steven H, Montgomery Ruth R
Abstract excerpt
Hepatitis C virus (HCV) is the most common chronic blood-borne infection in the United States, with the majority of patients becoming chronically infected and a subset (20%) progressing to cirrhosis and hepatocellular carcinoma. Individual variations in immune responses may help define successful resistance to infection with HCV. We have compared the immune response in primary macrophages from patients who have...
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