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Article

Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy.

Antiviral therapy - 1 Jan 2013

Huang Yi-Wen, Lin Shih-Chang, Wei Shu-Chen, Hu Jui-Ting, Chang Han-Yu, Huang Shih-Hung, Chen Ding-Shinn, Chen Pei-Jer, Hsu Ping-Ning, Yang Sien-Sing, Kao Jia-Horng

Abstract excerpt

BACKGROUND: Toll-like receptor (TLR)3 gene variants may correlate with clinical significance of chronic viral infections including HBV. We aimed to investigate the expression of TLR3 in peripheral blood mononuclear cells (PBMCs) and liver cells of chronic hepatitis B (CHB) patients and its response to pegylated interferon or nucleoside analogue therapy. METHODS: We consecutively enrolled 127 CHB patients and 64...

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Source

Identifiers

PMID: 23744559
DOI: 10.3851/IMP2630

Genes

TLR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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