Article
Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection.
Proceedings of the National Academy of Sciences of the United States of America - 5 Apr 2011
Dring Megan M, Morrison Maria H, McSharry Brian P, Guinan Kieran J, Hagan Richard, O'Farrelly Cliona, Gardiner Clair M
Abstract excerpt
Hepatitis C is a common infection with significant morbidity and mortality, and only a minority of patients successfully clear the infection. Identification of factors that influence disease progression in HCV infection is difficult owing to the lack of well-defined patient cohorts. However, recent evidence supports a role for the innate immune system in virus clearance. In this study, we investigated innate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.