Article
TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C.
Journal of medical virology - 1 Jul 2009
Askar Eva, Bregadze Rusudan, Mertens Jasmin, Schweyer Stefan, Rosenberger Albert, Ramadori Giuliano, Mihm Sabine
Abstract excerpt
Phenotypes of liver disease due to chronic hepatitis C virus (HCV) infection show a wide range of variations in terms of histological manifestations and the clinical outcome. Sensing of viral double-stranded RNA (dsRNA) by Toll-like receptor 3 (TLR3) is likely involved in early pathogen detection and the host response to viral infection. This study analyzed epidemiological and clinical data from a total of 137...
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