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Article

Intrahepatic TLR3 and IFNL3 Expressions Are Associated with Stages of Fibrosis in Chronic Hepatitis C.

Viruses - 9 Jun 2021

Guedes de Sá Keyla Santos, Amoras Ednelza da Silva Graça, Conde Simone Regina Souza da Silva, Queiroz Maria Alice Freitas, Cayres-Vallinoto Izaura Maria Vieira, Ishak Ricardo, Vallinoto Antonio Carlos Rosário

Abstract excerpt

An inefficient immune response against the hepatitis C virus (HCV), combined with viral evasion mechanisms, is responsible for the chronicity of infection. The need to evaluate the innate mechanisms of the immune response, such as TLR3 and IFN-λ3, and their relationship with the virus-host interaction is important for understanding the pathogenesis of chronic hepatitis C. The present study aimed to investigate...

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Identifiers

PMID: 34207750
DOI: 10.3390/v13061103
PMCID: PMC8230343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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