Article
Modulation of TLR 3, 7 and 8 expressions in HCV genotype 3 infected individuals: potential correlations of pathogenesis and spontaneous clearance.
BioMed research international - 1 Jan 2014
Firdaus Rushna, Biswas Aritra, Saha Kallol, Mukherjee Anirban, Pal Falguni, Chaudhuri Sujit, Chandra Alok, Konar Asokananda, Sadhukhan Provash Chandra
Abstract excerpt
BACKGROUND: Hepatitis C virus is the major cause of chronic hepatitis worldwide which finally leads to the development of hepatocellular carcinoma. Toll like receptors (TLRs) play an important role in the course of many viral infections, but the role of TLRs in HCV pathogenesis has not been well elucidated so far. OBJECTIVE: The aim of this study was to analyse the mRNA expression of TLRs 3, 7, and 8 in different...
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