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Article

Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle provides insights into the evolution of the cotranslational insertion systems.

The FEBS journal - 1 Feb 2013

Funes Soledad, Westerburg Heike, Jaimes-Miranda Fabiola, Woellhaf Michael W, Aguilar-Lopez Jose L, Janßen Linda, Bonnefoy Nathalie, Kauff Frank, Herrmann Johannes M

Abstract excerpt

The biogenesis of hydrophobic membrane proteins involves their cotranslational membrane integration in order to prevent their unproductive aggregation. In the cytosol of bacteria and eukaryotes, membrane targeting of ribosomes that synthesize membrane proteins is achieved by signal recognition particles (SRPs) and their cognate membrane-bound receptors. As is evident from the genomes of fully sequenced...

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Identifiers

PMID: 23198851
DOI: 10.1111/febs.12082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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