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Article

Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria.

The Journal of biological chemistry - 5 Oct 2012

Keil Melanie, Bareth Bettina, Woellhaf Michael W, Peleh Valentina, Prestele Martin, Rehling Peter, Herrmann Johannes M

Abstract excerpt

The terminal enzyme of the respiratory chain, cytochrome c oxidase, consists of a hydrophobic reaction center formed by three mitochondrially encoded subunits with which 9-10 nuclear encoded subunits are associated. The three core subunits are synthesized on mitochondrial ribosomes and inserted into the inner membrane in a co-translational reaction facilitated by the Oxa1 insertase. Oxa1 consists of an N-terminal...

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Identifiers

PMID: 22904327
DOI: 10.1074/jbc.M112.382630
PMCID: PMC3464553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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