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Article

Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function.

Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2009

Funes Soledad, Hasona Adnan, Bauerschmitt Heike, Grubbauer Caroline, Kauff Frank, Collins Ryan, Crowley Paula J, Palmer Sara R, Brady L Jeannine, Herrmann Johannes M

Abstract excerpt

YidC/Oxa/Alb3 family proteins catalyze the insertion of integral membrane proteins in bacteria, mitochondria, and chloroplasts, respectively. Unlike gram-negative organisms, gram-positive bacteria express 2 paralogs of this family, YidC1/SpoIIIJ and YidC2/YgjG. In Streptococcus mutans, deletion of yidC2 results in a stress-sensitive phenotype similar to that of mutants lacking the signal recognition particle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19366667
DOI: 10.1073/pnas.0809951106
PMCID: PMC2672490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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