Article
A mutational analysis reveals new functional interactions between domains of the Oxa1 protein in Saccharomyces cerevisiae.
Molecular microbiology - 1 Jan 2010
Mathieu Lise, Bourens Myriam, Marsy Sophie, Hlavacek Otakar, Panozzo Cristina, Dujardin Geneviève
Abstract excerpt
The Oxa1/YidC/Alb3 family plays a key role in the biogenesis of the respiratory and photosynthetic complexes in bacteria and organelles. In Saccharomyces cerevisiae, Oxa1 mediates the co-translational insertion of mitochondrially encoded subunits of the three respiratory complexes III, IV and V within the inner membrane and also controls a late step in complex V assembly. No crystal structure of YidC or Oxa1 is...
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