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Article

Differential relationship of DNA replication timing to different forms of human mutation and variation.

American journal of human genetics - 7 Dec 2012

Koren Amnon, Polak Paz, Nemesh James, Michaelson Jacob J, Sebat Jonathan, Sunyaev Shamil R, McCarroll Steven A

Abstract excerpt

Human genetic variation is distributed nonrandomly across the genome, though the principles governing its distribution are only partially known. DNA replication creates opportunities for mutation, and the timing of DNA replication correlates with the density of SNPs across the human genome. To enable deeper investigation of how DNA replication timing relates to human mutation and variation, we generated a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23176822
DOI: 10.1016/j.ajhg.2012.10.018
PMCID: PMC3516607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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