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Article

Complex correlations: replication timing and mutational landscapes during cancer and genome evolution.

Current opinion in genetics & development - 1 Apr 2014

Sima Jiao, Gilbert David M

Abstract excerpt

A recent flurry of reports correlates replication timing (RT) with mutation rates during both evolution and cancer. Specifically, point mutations and copy number losses correlate with late replication, while copy number gains and other rearrangements correlate with early replication. In some case...

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Identifiers

PMID: 24598232
DOI: 10.1016/j.gde.2013.11.022
PMCID: PMC4140690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24598232-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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