Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemia

22 Nov 2012

Abstract excerpt

The frequent occurrence of persistent or relapsed disease after induction chemotherapy in AML necessitates a better understanding of the clonal relationship of AML in various disease phases. In this study, we used SNP 6.0 array-based genomic profiling of acquired copy number aberrations (aCNA) and copy neutral LOH (cnLOH) together with sequence analysis of recurrently mutated genes to characterize paired AML...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Advanced biosensing and bioanalysis techniques
Share to Multiple Myeloma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23175688
DOI: 10.1182/blood-2012-04-427039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemiaPMID 23175688Read ↗

Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemiaSemantic proximity Read ↗

Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell GenomicsSemantic proximity Read ↗

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencingSemantic proximity Read ↗

Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?Semantic proximity Read ↗

Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia?Semantic proximity Read ↗

Clonal Evolution in 207 Cases of Refractory or Relapsed Acute Myeloid Leukemia.Semantic proximity Read ↗

Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia.Semantic proximity Read ↗

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.Semantic proximity Read ↗

Clonal evolution of acute leukemia genomes.Semantic proximity Read ↗

Genomic and evolutionary portraits of disease relapse in acute myeloid leukemiaSemantic proximity Read ↗

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Convergent epigenetic evolution drives relapse in acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.