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Article

Evaluation of genotypic prediction of HIV-1 tropism using population sequencing of replicates.

Journal of virological methods - 1 Feb 2012

Ferreira Joao Leandro de Paula, Coelho Luana Portes Ozorio, Rodrigues Rosangela, Cabral Gabriela Bastos, Cavalcanti Jaqueline de Souza, Guimaraes Paula Morena de Souza, Brigido Luis Fernando de Macedo

Abstract excerpt

Determination of human immunodeficiency virus tropism has contributed to the understanding of the pathogenesis of HIV and is necessary prior to the use of CCR5 antagonists. Replicate V3 sequences may generate different sequences and improve viral tropism prediction. The diversity of HIV was evaluated to access its influence on prediction. Plasma RNA was retro-transcribed and amplified using a one-step protocol,...

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Share to Cluster Analysis
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Viral

Share to Sequence Analysis, DNA

Share to Viral Tropism

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Source

Identifiers

PMID: 22138669
DOI: 10.1016/j.jviromet.2011.11.018

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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