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Article

Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies.

AIDS (London, England) - 23 Oct 2010

McGovern Rachel A, Thielen Alexander, Mo Theresa, Dong Winnie, Woods Conan K, Chapman Douglass, Lewis Marilyn, James Ian, Heera Jayvant, Valdez Hernan, Harrigan P Richard

Abstract excerpt

BACKGROUND: The MOTIVATE-1 and 2 studies compared maraviroc (MVC) along with optimized background therapy (OBT) vs. placebo along with OBT in treatment-experienced patients screened as having R5-HIV (original Monogram Trofile). A subset screened with non-R5 HIV were treated with MVC or placebo along with OBT in a sister safety trial, A4001029. This analysis retrospectively examined the performance of...

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PMID: 20736814
DOI: 10.1097/QAD.0b013e32833e6cfb

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