Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence.

doi:10.1186/1471-2350-10-26

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Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence.

BMC medical genetics - 13 Mar 2009

Chu Xun, Dong Yan, Shen Min, Sun Lingling, Dong Changzheng, Wang Yi, Wang Beilan, Zhang Kaiyue, Hua Qi, Xu Shijie, Huang Wei

Abstract excerpt

BACKGROUND: The beta-2-Adrenergic receptor (ADRB2) gene on chromosome 5q33.1 is an important immunoregulatory factor. We and others have previously implicated chromosomal region 5q31-33 for contribution to the genetic susceptibility to Graves disease (GD) in East-Asian populations. Two recent studies showed associations between the single nucleotide polymorphism (SNP) rs1042714 in the ADRB2 gene and GD. In this...

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PMID: 19284637
DOI: 10.1186/1471-2350-10-26
PMCID: PMC2666670

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ADRB2

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