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Association study of interleukin-12A gene polymorphisms with Graves' disease in two Chinese populations.

Clinical endocrinology - 1 Jan 2011

Guo Ting, Yang Shuyu, Liu Nan, Wang Shu, Cui Bin, Ning Guang

Abstract excerpt

OBJECTIVE: Graves' disease (GD) is a common autoimmune disorder and genetic and environmental factors contributing to its aetiology. The pro-inflammatory cytokine interleukin-12 (IL-12) is believed to be critically involved in the pathogenesis of GD. This study aims to elucidate the effect of IL-12A gene polymorphisms on GD. DESIGN AND METHODS: A case-control association study of five tag single nucleotide...

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PMID: 21044109
DOI: 10.1111/j.1365-2265.2010.03905.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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