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Article

Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.

Clinical endocrinology - 1 May 2004

Collins J E, Heward J M, Nithiyananthan R, Nejentsev S, Todd J A, Franklyn J A, Gough S C L

Abstract excerpt

OBJECTIVE: Vitamin D modulates the immune system by suppressing the proliferation of activated T cells, with its actions being directed through the vitamin D receptor (VDR). A number of single nucleotide polymorphisms (SNPs) have been identified in the VDR gene, of which several have been associated with autoimmune diseases, including type 1 diabetes and Graves' disease (GD) in Japanese females. The aim of this...

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Identifiers

PMID: 15104566
DOI: 10.1111/j.1365-2265.2004.02015.x

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.PMID 15104566Read ↗

Vitamin D receptor (VDR) gene polymorphisms and Graves' disease: a meta-analysis.Semantic proximity Read ↗

Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population.Semantic proximity Read ↗

Lack of association between the IL-13 C-1112T, G2044A polymorphisms and Graves' disease risk: evidence from a meta-analysis.Semantic proximity Read ↗

Dense mapping of IL2RA shows no association with Graves' disease in Chinese Han population.Semantic proximity Read ↗

Tag SNP screening of the PDCD1 gene for association with Graves' disease.Semantic proximity Read ↗

Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.Semantic proximity Read ↗

A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians.Semantic proximity Read ↗

Polymorphisms of interleukin 4 receptor gene and interleukin 10 gene are not associated with Graves' disease in the UK.Semantic proximity Read ↗

Association between vitamin-D receptor gene FokI polymorphism and Graves' disease among Taiwanese Chinese.Semantic proximity Read ↗

Lack of association of VDR gene polymorphisms with thyroid autoimmune disorders: familial and case/control studies.Semantic proximity Read ↗

Vitamin D receptor polymorphisms are associated with Graves' disease in German and Polish but not in Serbian patients.Semantic proximity Read ↗

Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.Semantic proximity Read ↗

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