Article
Identification of BACH2 as a susceptibility gene for Graves' disease in the Chinese Han population based on a three-stage genome-wide association study.
Human genetics - 1 May 2014
Liu Wei, Wang Hai-Ning, Gu Zhao-Hui, Yang Shao-Ying, Ye Xiao-Ping, Pan Chun-Ming, Zhao Shuang-Xia, Xue Li-Qiong, Xie Hui-Jun, Yu Sha-Sha, Guo Cui-Cui, Du Wen-Hua, Liang Jun, Zhang Xiao-Mei, Yuan Guo-Yue, Li Chang-Gui, Su Qing, Gao Guan-Qi, Song Huai-Dong
Abstract excerpt
The BACH2 gene regulates B cell differentiation and function and has been reported to be a shared susceptibility gene for several autoimmune diseases. Our previous genome-wide association study (GWAS) indicated that several single nucleotide polymorphisms (SNPs) in the BACH2 gene are associated with Graves' disease (GD) in the Chinese Han population; however, the association did not achieve genome-wide...
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