Article
ITM2A Expands Evidence for Genetic and Environmental Interaction in Graves Disease Pathogenesis.
The Journal of clinical endocrinology and metabolism - 1 Feb 2017
Ye Xiao-Ping, Yuan Fei-Fei, Zhang Le-Le, Ma Yu-Ru, Zhang Man-Man, Liu Wei, Sun Feng, Wu Jing, Lu Meng, Xue Li-Qiong, Shi Jing-Yi, Zhao Shuang-Xia, Song Huai-Dong, Liang Jun, Zheng Cui-Xia
Abstract excerpt
Context: Graves disease (GD) is a common autoimmune disease triggered by genetic predisposition and environmental factors. However, the mechanisms of interaction between genetic and environmental factors contributing to the development of GD remain unknown. Objective: We aimed to identify GD susceptibility variants and genes on Xq21.1 locus and interpret the contribution of interaction between genetic...
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