Article
Association of IL12B polymorphisms with susceptibility to Graves ophthalmopathy in a Taiwan Chinese population.
Journal of biomedical science - 19 Nov 2012
Liu Yu-Huei, Chen Ching-Chu, Liao Li-Ling, Wan Lei, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: Interleukin 12B (IL12B) gene polymorphisms have been linked to several inflammatory diseases, but their role in the development of Graves ophthalmopathy (GO) in Graves disease (GD) patients is unclear. The purpose of this study was to investigate the disease association of IL12B single nucleotide polymorphisms (SNPs). METHODS: A Taiwan Chinese population comprising 200 GD patients with GO and 271 GD...
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