Article
Genetic association between IL-17F gene polymorphisms and the pathogenesis of Graves' Disease in the Han Chinese population.
Gene - 10 Jan 2013
Guo Ting, Huo Ya'nan, Zhu Wei, Xu Fanghua, Liu Changqin, Liu Nan, Cao Min, Cui Bin, Ning Guang
Abstract excerpt
BACKGROUND: Graves' Disease (GD) is a common and complex disorder, with a strong hereditary component. IL-17F is a potent cytokine and a potential contributor to the etiology of various human autoimmune diseases. In the present study, we focused on the relationship between polymorphisms in the IL-17F gene and GD susceptibility through a case-control association study in two independent Chinese cohorts. METHODS:...
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