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Article

Genetic susceptibility to Graves' ophthalmopathy: the role of polymorphisms in proinflammatory cytokine genes.

Eye (London, England) - 1 Jun 2010

Anvari M, Khalilzadeh O, Esteghamati A, Esfahani S A, Rashidi A, Etemadi A, Mahmoudi M, Amirzargar A A

Abstract excerpt

PURPOSE: In order to investigate the underlying genetic mechanisms of Graves' ophthalmopathy (GO), we examined the association between single-nucleotide polymorphisms in five important proinflammatory cytokines, namely IL-12, TNF-alpha, IFN-gamma, IL-2, and IL-6, with GO in a sample of Iranian adults. METHODS: A total of 57 patients with Graves' disease without GO, 50 patients with GO, and 140 healthy controls...

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PMID: 19798110
DOI: 10.1038/eye.2009.244

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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