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Article

Association of interleukin-16 polymorphisms with graves' disease in a Taiwanese population.

The Chinese journal of physiology - 30 Apr 2014

Tsai Kun-Hsi, Chang Ching-Yao, Tsai Fuu-Jen, Lin Hui-Ju, Yang Yuh-Shyong, Lim Yun-Ping, Liao Chiu-Chu, Wan Lei

Abstract excerpt

Graves' disease (GD) is a complex, organ-specific autoimmune disease wherein the thyroid gland becomes enlarged and overactive. During GD progression, T cells secrete interleukin-16 (IL-16) to promote inflammation, act as chemoattractants that recruit more inflammatory cells, and activate target cells to enhance the development of GD. To investigate the role of IL-16 in GD, we genotyped 474 patients with GD at 8...

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Identifiers

PMID: 24694201
DOI: 10.4077/CJP.2014.BAB150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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