Article
IL-17 and IL-38 gene polymorphisms in thyroid-associated ophthalmopathy.
International ophthalmology - 18 Sept 2024
Mussakulova Ainura, Balmukhanova Altynay, Aubakirova Alua, Khamdiyeva Ozada, Zhunussova Gulnur, Balmukhanova Aigul
Abstract excerpt
BACKGROUND: Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition commonly linked with Graves' disease (GD), characterized by orbital tissue inflammation and fibrosis. It is hypothesized that gene polymorphisms may influence production of the IL-17 and IL-38 cytokines, thereby impacting TAO development and progression. This study focused on investigating the gene polymorphisms of IL-17 (rs9463772 C/T...
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