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Article

BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.

Carcinogenesis - 1 Feb 2013

Fernandez-Rozadilla Ceres, Palles Claire, Carvajal-Carmona Luis, Peterlongo Paolo, Nici Carmela, Veneroni Silvia, Pinheiro Manuela, Teixeira Manuel R, Moreno Victor, Lamas Maria-Jesus, Baiget Montserrat, Lopez-Fernandez L A, Gonzalez Dolors, Brea-Fernandez Alejandro, Clofent Juan, Bujanda Luis, Bessa Xavier, Andreu Montserrat, Xicola Rosa, Llor Xavier, Jover Rodrigo, Castells Antoni, Castellvi-Bel Sergi, Carracedo Angel, Tomlinson Ian, Ruiz-Ponte Clara

Abstract excerpt

Genome-wide association studies have successfully identified 20 colorectal cancer susceptibility loci. Amongst these, four of the signals are defined by tagging single nucleotide polymorphisms (SNPs) on regions 14q22.2 (rs4444235 and rs1957636) and 20p12.3 (rs961253 and rs4813802). These markers are located close to two of the genes involved in bone morphogenetic protein (BMP) signaling (BMP4 and BMP2,...

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Source

Identifiers

PMID: 23161572
DOI: 10.1093/carcin/bgs357

Genes

BMP2
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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