Article
A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.
Carcinogenesis - 1 Nov 2014
Schmit Stephanie L, Schumacher Fredrick R, Edlund Christopher K, Conti David V, Raskin Leon, Lejbkowicz Flavio, Pinchev Mila, Rennert Hedy S, Jenkins Mark A, Hopper John L, Buchanan Daniel D, Lindor Noralane M, Le Marchand Loic, Gallinger Steven, Haile Robert W, Newcomb Polly A, Huang Shu-Chen, Rennert Gad, Casey Graham, Gruber Stephen B
Abstract excerpt
Only a fraction of colorectal cancer heritability is explained by known risk-conferring genetic variation. This study was designed to identify novel risk alleles in Europeans. We conducted a genome-wide association study (GWAS) meta-analysis of colorectal cancer in participants from a population-based case-control study in Israel (n = 1616 cases, 1329 controls) and a consortium study from the Colon Cancer Family...
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