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Article

Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.

PloS one - 1 Jan 2012

Thean Lai Fun, Li Hui Hua, Teo Yik Ying, Koh Woon-Puay, Yuan Jian-Min, Teoh Mei Lin, Koh Poh Koon, Tang Choong Leong, Cheah Peh Yean

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) in Caucasians have identified fourteen index single nucleotide polymorphisms (iSNPs) that influence colorectal cancer (CRC) risk. METHODS: We investigated the role of eleven iSNPs or surrogate SNPs (sSNPs), in high linkage disequilibrium (LD, r(2)≥ 0.8) and within 100 kb vicinity of iSNPs, in 2,000 age- and gender-matched Singapore Chinese (SCH) cases and...

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Identifiers

PMID: 22879968
DOI: 10.1371/journal.pone.0042407
PMCID: PMC3411754

Genes

BMP2
BMP4
GREM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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