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Article

Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.

PloS one - 9 Sept 2010

Fernández-Rozadilla Ceres, de Castro Luisa, Clofent Juan, Brea-Fernández Alejandro, Bessa Xavier, Abulí Anna, Andreu Montserrat, Jover Rodrigo, Xicola Rosa, Llor Xavier, Castells Antoni, Castellví-Bel Sergi, Carracedo Angel, Ruiz-Ponte Clara

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is considered a complex disease, and thus the majority of the genetic susceptibility is thought to lie in the form of low-penetrance variants following a polygenic model of inheritance. Candidate-gene studies have so far been one of the basic approaches taken to identify these susceptibility variants. The consistent involvement of some signaling routes in carcinogenesis...

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PMID: 20844743
DOI: 10.1371/journal.pone.0012673
PMCID: PMC2936577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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