Article
Genome-wide association study of colorectal cancer in Hispanics.
Carcinogenesis - 1 Jun 2016
Schmit Stephanie L, Schumacher Fredrick R, Edlund Christopher K, Conti David V, Ihenacho Ugonna, Wan Peggy, Van Den Berg David, Casey Graham, Fortini Barbara K, Lenz Heinz-Josef, Tusié-Luna Teresa, Aguilar-Salinas Carlos A, Moreno-Macías Hortensia, Huerta-Chagoya Alicia, Ordóñez-Sánchez María Luisa, Rodríguez-Guillén Rosario, Cruz-Bautista Ivette, Rodríguez-Torres Maribel, Muñóz-Hernández Linda Liliana, Arellano-Campos Olimpia, Gómez Donají, Alvirde Ulices, González-Villalpando Clicerio, González-Villalpando María Elena, Le Marchand Loic, Haiman Christopher A, Figueiredo Jane C
Abstract excerpt
Genome-wide association studies (GWAS) have identified 58 susceptibility alleles across 37 regions associated with the risk of colorectal cancer (CRC) with P < 5×10(-8) Most studies have been conducted in non-Hispanic whites and East Asians; however, the generalizability of these findings and the potential for ethnic-specific risk variation in Hispanic and Latino (HL) individuals have been largely understudied....
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