Article
Genetic variation in bone morphogenetic protein and colon and rectal cancer.
International journal of cancer - 1 Feb 2012
Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Kadlubar Susan, Caan Bette J, Potter John D, Wolff Roger K
Abstract excerpt
Bone morphogenetic proteins (BMP) are part of the TGF-β-signaling pathway; genetic variation in these genes may be involved in colorectal cancer. In this study, we evaluated the association between genetic variation in BMP1 (11 tagSNPs), BMP2 (5 tagSNPs), BMP4 (3 tagSNPs), BMPR1A (9 tagSNPs), BMP...
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