Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies.

doi:10.1016/j.cyto.2014.12.021

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Article

Common genetic variant on BMP4 contributes to colorectal adenoma and cancer: A meta-analysis based on 15 studies.

Cytokine - 1 Apr 2015

Zhou Lei, Xie Jun, Gu Er-li, Huang Yao, Qu Yan, Xu Ai-Ping, Zhu Yin, Wang Hong

Abstract excerpt

Epidemiological studies indicate a genetic contribution to colorectal cancer (CRC), but specific genetic variants remain unknown. Genome-wide association studies have identified rs4444235 at BMP4 as a new colorectal cancer (CRC) and colorectal adenoma (CRA) susceptibility locus in populations of European descent. After that, several validation studies have been conducted among various ethnic populations to...

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PMID: 25647270
DOI: 10.1016/j.cyto.2014.12.021

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BMP4

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