Article
Detailed mapping of the Rfv-1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 1992
Miyazawa M, Nishio J, Wehrly K, Jay G, Melvold R W, Chesebro B
Abstract excerpt
Using H-2 recombinant and mutant mice, the Rfv-1 gene influencing spontaneous recovery from Friend retrovirus (FV)-induced leukaemia was mapped in the D locus. Two Db alleles were required for full recovery, and a single Dd transgene did not convey increased susceptibility to FV in the presence o...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Friend murine leukemia virus
- Genotype
- H-2 Antigens
- Haplotypes
- Leukemia, Experimental
- Mice
- Mice, Inbred Strains
- Mice, Transgenic
- T-Lymphocytes, Cytotoxic