Article
Recruitment of multiple alleles within the Eb recombinational hotspot in murine MHC.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Saha B K
Abstract excerpt
Genetic recombination has been proposed to have played a major role in generating the extensive polymorphism that distinguishes the genes of the major histocompatibility complex (MHC). The proximal region of the murine H-2 represents a unique segment of DNA encompassing at least four hotspots for...
Topics
- Alleles
- Animals
- Base Sequence
- Crosses, Genetic
- DNA
- Female
- H-2 Antigens
- Humans
- Major Histocompatibility Complex
- Male
- Mice
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Recombination, Genetic
- Restriction Mapping
- Sequence Homology, Nucleic Acid
