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Article

Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus.

RNA (New York, N.Y.) - 1 Jan 2013

Nishi Kenji, Nishi Ai, Nagasawa Tatsuya, Ui-Tei Kumiko

Abstract excerpt

GW182 family proteins play important roles in microRNA (miRNA)-mediated gene silencing. They interact with Argonaute (Ago) proteins and localize in processing bodies, which are cytoplasmic foci involved in mRNA degradation and storage. Here, we demonstrated that human GW182 paralog, TNRC6A, is a nuclear-cytoplasmic shuttling protein, and its subcellular localization is conducted by a nuclear export signal (NES)...

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23150874
DOI: 10.1261/rna.034769.112
PMCID: PMC3527724

Genes

NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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