Article
<i>Wolbachia</i>interferes with the intracellular distribution of Argonaute 1 in the dengue vector<i>Aedes aegypti</i>by manipulating the host microRNAs
1 Dec 2013
Abstract excerpt
Argonaute proteins (AGOs) are vital components of the RNA-induced silencing complex in gene silencing. AGOs are indispensable for microRNA (miRNA) biogenesis as well as function, and are intracellularly localized to both the cytoplasm and the nucleus. Cytoplasmic AGO-miRNA complexes are mainly involved in cleavage or translational repression of target mRNAs while the nuclear ones are engaged in transcriptional...
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