Article

RAVER1 interconnects lethal EMT and miR/RISC activity by the control of alternative splicing

2023-06-14

Abstract excerpt

The RAVER1 protein was proposed to serve as a co-factor in guiding the PTBP-dependent control of alternative splicing (AS). Whether RAVER1 solely acts in concert with PTBPs and how it affects cancer cell fate remained elusive. Here we provide the first comprehensive investigation of RAVER1-controlled AS in cancer cell models and reveal a pro-oncogenic role of RAVER1 in tumor growth. This unravels that RAVER1 guide...

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Literature Corpus work: 84fa1faf-c1f4-523e-963f-8730b610066e
DOI: 10.1101/2023.06.14.544976

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