Article
Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.
The Journal of cell biology - 31 Jul 2006
Schneider Mary D, Najand Nima, Chaker Sana, Pare Justin M, Haskins Julie, Hughes Sarah C, Hobman Tom C, Locke John, Simmonds Andrew J
Abstract excerpt
In mammalian cells, the GW182 protein localizes to cytoplasmic bodies implicated in the regulation of messenger RNA (mRNA) stability, translation, and the RNA interference pathway. Many of these functions have also been assigned to analogous yeast cytoplasmic mRNA processing bodies. We have characterized the single Drosophila melanogaster homologue of the human GW182 protein family, which we have named Gawky...
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