Article
Functional dissection of the human TNRC6 (GW182-related) family of proteins.
Molecular and cellular biology - 1 Aug 2009
Baillat David, Shiekhattar Ramin
Abstract excerpt
Argonaute (Ago) proteins through their association with small RNAs perform a critical function in the effector step of RNA interference. The TNRC6 (trinucleotide repeat containing 6) family of proteins have been shown to stably associate with Agos in mammalian cells. Here, we describe the isolation and functional characterization of TNRC6B- and TNRC6C-containing complexes. We show that TNRC6B and TNRC6C proteins...
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