Article
TNFA promoter alleles--frequencies and linkage with classical HLA genes in a South German Caucasian population.
Tissue antigens - 1 Dec 2012
Fürst D, Zollikofer Ch, Schrezenmeier H, Mytilineos J
Abstract excerpt
The tumor necrosis factor alpha (TNFA) promoter region exhibits several polymorphisms, which have been hypothesized to influence gene expression, thereby associating positively or negatively with inflammatory conditions. Many studies have focused on single nucleotide polymorphisms (SNPs) taking not into account additive or inverse effects between different SNPs. We typed 1,021 healthy Caucasian volunteer stem...
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