Functional analysis of a new polymorphism in the human TNF alpha gene promoter.

doi:10.1111/j.1365-3083.1995.tb03686.x

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Article

Functional analysis of a new polymorphism in the human TNF alpha gene promoter.

Scandinavian journal of immunology - 1 Oct 1995

Pociot F, D'Alfonso S, Compasso S, Scorza R, Richiardi P M

Abstract excerpt

In this paper the functional relevance of a TNFA promoter polymorphism, a G/A polymorphic sequence at position -238, was tested by analysing its influence on TNF alpha production upon in vitro stimulation of monocytes from 78 healthy, unrelated individuals by lipopolysaccharide (LPS) or after all...

Topics

Adolescent
Adult
Alleles
Humans
Male
Polymorphism, Genetic
Promoter Regions, Genetic
Tumor Necrosis Factor-alpha

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